How did it end?

Pope Clement VI left his court in Avignon, France for estate called Chateau-nauf. He is said to have sat by a great fireplace in his manor house, praying that the fire would keep away the disease. Perhaps it worked, Clement survived the Plague. It died, although it reappeared over the next three centuries. Improvements in sanitary conditions helped. Drugs helped out as well. They started practicing proper hygiene. People would stay in their houses and only leave if they had to get food or for something else.